
Here's what Plugin Alliance are saying about some of the incompatibility between some plugins and macOS Sierra 10.12:
Mac sierra good for 2011 mac os#
(Sigh: seems like we have similar issues every new Mac OS release.). Unfortunately, there appears to be a problem with certain audio unit plugins running in Apple's new OS. Yes, it's lovely to delve into new OS features. Yes, we know you want to experience Siri on your Mac. But, just as macOS Sierra is launching around 22nd September.

By the time you read this it might (and probably will be) safe to upgrade. At least don't upgrade to the first version of macOS Sierra on your primary music making machine.

ARTICLE UPDATE: Anyone who has updated to macOS Sierra 10.12 and is experiencing difficulty with UA or Plugin Alliance or any apparently unsupported AU plugins and drivers, please click here to read about a possible workaround to fix things.
